Anti-Vascular Endothelial Growth Factors as a Potential Risk for Implant Failure: A Clinical Report
Knowledge of the risk factors for implant osseointegration is essential for clinical decision-making and optimizing treatment success. This clinical report presents a rare case of implant failure in a patient who received intravitreal injections of a vascular endothelial growth factor (VEGF) inhibit...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2020-01-01
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| Series: | Case Reports in Medicine |
| Online Access: | http://dx.doi.org/10.1155/2020/6141493 |
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| _version_ | 1832554395367112704 |
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| author | Elham Emami Pierre de Grandmont Mélanie Menassa Nicholas Audy Robert Durand |
| author_facet | Elham Emami Pierre de Grandmont Mélanie Menassa Nicholas Audy Robert Durand |
| author_sort | Elham Emami |
| collection | DOAJ |
| description | Knowledge of the risk factors for implant osseointegration is essential for clinical decision-making and optimizing treatment success. This clinical report presents a rare case of implant failure in a patient who received intravitreal injections of a vascular endothelial growth factor (VEGF) inhibitor for the treatment of age-related macular degeneration. Following CARE guidelines, the report presents a case rehabilitated with a mandibular 2-implant overdenture using the immediate-loading protocol and standard procedures. The implants failed within six weeks of immediate loading although primary stability (≥50 Ncm) was achieved during surgery and clinical follow-ups did not show any deviance from standard implant care or patient-related complications. Further investigation suggested that the intake of a VEGF inhibitor may be the cause of failure. This clinical report highlights the importance of systemic risk factors in implant success and their consideration during planning for implant-assisted treatment. |
| format | Article |
| id | doaj-art-e10ddbde7aea4081aedb7b8bb52f0c5c |
| institution | Kabale University |
| issn | 1687-9627 1687-9635 |
| language | English |
| publishDate | 2020-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Medicine |
| spelling | doaj-art-e10ddbde7aea4081aedb7b8bb52f0c5c2025-02-03T05:51:45ZengWileyCase Reports in Medicine1687-96271687-96352020-01-01202010.1155/2020/61414936141493Anti-Vascular Endothelial Growth Factors as a Potential Risk for Implant Failure: A Clinical ReportElham Emami0Pierre de Grandmont1Mélanie Menassa2Nicholas Audy3Robert Durand4Faculty of Dentistry, McGill University, Montreal, QC, CanadaFaculty of Dentistry, Université de Montréal, Montreal, QC, CanadaFaculty of Dentistry, Université de Montréal, Montreal, QC, CanadaPrivate Clinic, Saint-Jérôme, QC, CanadaFaculty of Dentistry, Université de Montréal, Montreal, QC, CanadaKnowledge of the risk factors for implant osseointegration is essential for clinical decision-making and optimizing treatment success. This clinical report presents a rare case of implant failure in a patient who received intravitreal injections of a vascular endothelial growth factor (VEGF) inhibitor for the treatment of age-related macular degeneration. Following CARE guidelines, the report presents a case rehabilitated with a mandibular 2-implant overdenture using the immediate-loading protocol and standard procedures. The implants failed within six weeks of immediate loading although primary stability (≥50 Ncm) was achieved during surgery and clinical follow-ups did not show any deviance from standard implant care or patient-related complications. Further investigation suggested that the intake of a VEGF inhibitor may be the cause of failure. This clinical report highlights the importance of systemic risk factors in implant success and their consideration during planning for implant-assisted treatment.http://dx.doi.org/10.1155/2020/6141493 |
| spellingShingle | Elham Emami Pierre de Grandmont Mélanie Menassa Nicholas Audy Robert Durand Anti-Vascular Endothelial Growth Factors as a Potential Risk for Implant Failure: A Clinical Report Case Reports in Medicine |
| title | Anti-Vascular Endothelial Growth Factors as a Potential Risk for Implant Failure: A Clinical Report |
| title_full | Anti-Vascular Endothelial Growth Factors as a Potential Risk for Implant Failure: A Clinical Report |
| title_fullStr | Anti-Vascular Endothelial Growth Factors as a Potential Risk for Implant Failure: A Clinical Report |
| title_full_unstemmed | Anti-Vascular Endothelial Growth Factors as a Potential Risk for Implant Failure: A Clinical Report |
| title_short | Anti-Vascular Endothelial Growth Factors as a Potential Risk for Implant Failure: A Clinical Report |
| title_sort | anti vascular endothelial growth factors as a potential risk for implant failure a clinical report |
| url | http://dx.doi.org/10.1155/2020/6141493 |
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