Pharmacology and metabolomic reveal Polysaccharides from polygonatum sibiricum ameliorate the diabetic osteoporosis in zebrafish

Pharmacology and metabolomic reveal Polysaccharides from polygonatum sibiricum ameliorate the diabetic osteoporosis in zebrafish

Abstract Background Previous studies found that Polygonatum sibiricum polysaccharide (PSP) exhibited anti-inflammatory and anti-oxidative effects on type 2 diabetes (T2DM). However, the roles and detailed mechanisms of PSP on the anti-diabetic osteoporosis are still poorly defined. The purpose of th...

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Bibliographic Details
Main Authors: Ziping Chen, Na Li, Zhou Zhou, Lin Zhu, Kai Wang, Shijin Chen, Quan Gu, Yujun Liu, Kefeng Zhai, Shuwen Xu
Format: Article
Language:English
Published: BMC 2025-07-01
Series:BMC Complementary Medicine and Therapies
Subjects:
Anti-diabetic
Metabolomics
Osteoporosis
Polysaccharide
Zebrafish
Online Access:https://doi.org/10.1186/s12906-025-04978-9
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https://doi.org/10.1186/s12906-025-04978-9

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