Efficacy and safety of ketamine and esketamine for preventing opioid-induced cough: a systematic review and meta-analysis of randomized controlled trials

Abstract Background Opioid-induced cough (OIC) is a common side effect during anesthetic induction. This systematic review and meta-analysis aimed to evaluate the efficacy and safety of ketamine/esketamine in preventing OIC during anesthetic induction. Methods We systematically searched Medline, Emb...

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Bibliographic Details
Main Authors: Kuo-Chuan Hung, Ting-Sian Yu, Chih-Wei Hsu, Wei-Cheng Liu, Jheng-Yan Wu, Shu-Wei Liao, Chien-Ming Lin, I.-Wen Chen
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Systematic Reviews
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Online Access:https://doi.org/10.1186/s13643-025-02886-0
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