Exploring the pathways linking fasting insulin to coronary artery disease: a proteome-wide Mendelian randomization study

Abstract Background Insulin is known to be associated with a higher risk of coronary artery disease (CAD), but molecular mechanisms remain unclear. This study aimed to explore protein-mediated pathways linking fasting insulin to CAD using Mendelian randomization (MR). Methods This MR study examined...

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Bibliographic Details
Main Authors: Xin Huang, Jie V. Zhao
Format: Article
Language:English
Published: BMC 2025-05-01
Series:BMC Medicine
Subjects:
Online Access:https://doi.org/10.1186/s12916-025-04127-6
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