Ellagic acid: A potent glyoxalase-I inhibitor with a unique scaffold
The glyoxalase system, particularly glyoxalase-I (GLO-I), has been approved as a potential target for cancer treatment. In this study, a set of structurally diverse polyphenolic natural compounds were investigated as potential GLO-I inhibitors. Ellagic acid was found, computationally and experimenta...
Saved in:
Main Authors: | Al-Shar’i Nizar A., Al-Balas Qosay A., Hassan Mohammad A., El-Elimat Tamam M., Aljabal Ghazi A., Almaaytah Ammar M. |
---|---|
Format: | Article |
Language: | English |
Published: |
Sciendo
2021-03-01
|
Series: | Acta Pharmaceutica |
Subjects: | |
Online Access: | https://doi.org/10.2478/acph-2021-0005 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Humic Acid Enhances Antioxidant and Glyoxalase Systems to Combat Copper Toxicity in Citrus
by: Wei-Tao Huang, et al.
Published: (2025-01-01) -
A novel cobalt oxide nanoparticle conjugated with ellagic acid arrests the cell cycle in human liver cancer cell line
by: Ayda Mahmoudi, et al.
Published: (2025-01-01) -
Ellagic acid ameliorates cisplatin-induced acute kidney injury by regulating inflammation and SIRT6/TNF-α signaling
by: Yuqi Gao, et al.
Published: (2023-11-01) -
Pharmacokinetics study of a supersaturatable self-microemulsifying drug delivery system for ellagic acid by UHPLC-Q-TOF-MS
by: Wang Jinglong, et al.
Published: (2021-12-01) -
Ellagic Acid from <i>Geranium thunbergii</i> and Antimalarial Activity of Korean Medicinal Plants
by: Hojong Jun, et al.
Published: (2025-01-01)