The effect of leflunomide on cycling and activation of T-cells in HIV-1-infected participants.

The effect of leflunomide on cycling and activation of T-cells in HIV-1-infected participants.

<h4>Background</h4>The pathogenesis of immunodeficiency due to human immunodeficiency virus (HIV)-1 is incompletely understood, but immune activation is believed to play a central role. Immunomodulatory agents that decrease immune activation may be useful in the treatment of HIV-1 infect...

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Main Authors: Sarah W Read, Mary DeGrezia, Emily J Ciccone, Rebecca DerSimonian, Jeanette Higgins, Joseph W Adelsberger, Judith M Starling, Catherine Rehm, Irini Sereti
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-08-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0011937&type=printable
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https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0011937&type=printable

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