Phenotypic Characterization of Subtype A and Recombinant AC Transmitted/Founder Viruses from a Rwandan HIV-1 Heterosexual Transmission Cohort

Phenotypic Characterization of Subtype A and Recombinant AC Transmitted/Founder Viruses from a Rwandan HIV-1 Heterosexual Transmission Cohort

HIV-1 subtypes have distinct geographical distributions, with subtypes A, C, and D and inter-subtype recombinants circulating in sub-Saharan Africa. Historically, individuals living with subtype A viruses exhibit slower CD4 decline and progression to AIDS diagnosis. Despite this, there are few authe...

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Bibliographic Details
Main Authors: Ling Yue, Rui Xu, Samantha Mclnally, Qianhong Qin, Jake W. Rhodes, Erick Muok, Gisele Umviligihozo, Kelsie Brooks, Jiayi Zhang, Zhaohui Qin, Jean Bizimana, Jonathan Hare, Matthew A. Price, Susan A. Allen, Etienne Karita, Eric Hunter
Format: Article
Language:English
Published: MDPI AG 2024-10-01
Series:Viruses
Subjects:
infectious molecular clone
IMC
virus replicative capacity
co-receptor usage
bNAb potency and breadth
Online Access:https://www.mdpi.com/1999-4915/16/11/1706
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