Cortisol regulates neonatal lung development via Smoothened

Cortisol regulates neonatal lung development via Smoothened

Abstract Background Neonatal respiratory distress syndrome (NRDS), one of the main causes of neonatal death, is clinically characterized by progressive dyspnea and cyanosis 1 to 2 h after birth. Corticosteroids are commonly used to prevent NRDS in clinical. However, the protective mechanism of the c...

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Main Authors: Shanshan Lu, Yifei Chen, Jiawen Song, Liangliang Ren, Jun Du, Donglai Shen, Jiayin Peng, Yao Yin, Xia Li, Yuqing Wang, Yan Gao, Siman Han, Yichang Jia, Yun Zhao, Yizheng Wang
Format: Article
Language:English
Published: BMC 2025-01-01
Series:Respiratory Research
Subjects:
Neonatal respiratory distress syndrome
Lung development
Cortisol
SHH pathway
Online Access:https://doi.org/10.1186/s12931-025-03104-0
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