Variants of creating heterotopic and orthotopic PDX models of human colorectal cancer

Variants of creating heterotopic and orthotopic PDX models of human colorectal cancer

Aim. To create heterotopic and orthotopic patient-derived xenograft (PDX) models of colorectal cancer (CRC) by transplantation of patient’s tumor samples into immunodeficient BALB / c Nude mice.Materials and methods. The study was performed on 15 female BALB / c Nude mice aged 6–8 weeks weighing 21–...

Full description

Saved in:
Bibliographic Details
Main Authors: A. A. Kiblitskaya, A. Y. Maksimov, A. S. Goncharova, Ye. M. Nepomnyashchaya, Ye. Y. Zlatnik, G. Y. Yegorov, Ye. A. Lukbanova, Ye. V. Zaikina, A. V. Volkova
Format: Article
Language:English
Published: Siberian State Medical University (Tomsk) 2022-10-01
Series:Бюллетень сибирской медицины
Subjects:
pdx model
xenograft
colorectal cancer
adenocarcinoma
orthotopic transplantation
heterotopic transplantation
balb / с nude
Online Access:https://bulletin.ssmu.ru/jour/article/view/4905
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://bulletin.ssmu.ru/jour/article/view/4905

Similar Items