Shedding light on the DICER1 mutational spectrum of uncertain significance in malignant neoplasms

The Dicer protein is an indispensable player in such fundamental cell pathways as miRNA biogenesis and regulation of protein expression in a cell. Most recently, both germline and somatic mutations in DICER1 have been identified in diverse types of cancers, which suggests Dicer mutations can lead to...

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Bibliographic Details
Main Authors: D. S. Bug, I. S. Moiseev, Yu. B. Porozov, N. V. Petukhova
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-10-01
Series:Frontiers in Molecular Biosciences
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Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2024.1441180/full
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