Effect of degeneration stage on non-viral tissue transfection of rd10 retina ex vivo

Gene therapy has great potential for the treatment of inherited retinal diseases, as evidenced by the progress and ongoing research. Using the Sleeping Beauty (SB) transposon system, we developed a non-viral gene delivery system for electroporation-based transfection of rd10 retinas ex vivo. SB100X...

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Bibliographic Details
Main Authors: Jiao Zhang, Ziyu Bing, Corinne Marie, Zsuzsanna Izsvák, Frank Müller, Gabriele Thumann, Peter Walter, Sandra Johnen
Format: Article
Language:English
Published: Elsevier 2025-09-01
Series:Molecular Therapy: Nucleic Acids
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Online Access:http://www.sciencedirect.com/science/article/pii/S2162253125001702
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