ADP-ribose hydrolases: biological functions and potential therapeutic targets

ADP-ribosylation (ADPRylation), which encompasses poly(ADP-ribosyl)ation and mono(ADP-ribosyl)ation, is an important post-translational modification catalysed by the poly(ADP-ribose) polymerase (PARP) enzyme superfamily. The process involves writers (PARPs) and erasers (ADP-ribose hydrolases), which...

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Bibliographic Details
Main Authors: Jingpeng Wang, Zhao-Qi Wang, Wen Zong
Format: Article
Language:English
Published: Cambridge University Press 2024-01-01
Series:Expert Reviews in Molecular Medicine
Subjects:
Online Access:https://www.cambridge.org/core/product/identifier/S1462399424000176/type/journal_article
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