Quality of life and clinical correlates in cognitively-able autistic adults: A special focus on sensory characteristics and perceived parental support

Background: Quality of life (QoL) has been suggested as an indicator of outcomes in autistic adults. Factors associated with QoL in autistic individuals remain unclear. This study aims to examine the subjective QoL for autistic adults in Taiwan and investigate the determinants for different domains...

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Main Authors: Chun-Yi Lin, Yi-Lun Wu, Yi-Ling Chien, Susan Shur-Fen Gau
Format: Article
Language:English
Published: Elsevier 2025-02-01
Series:Journal of the Formosan Medical Association
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Online Access:http://www.sciencedirect.com/science/article/pii/S0929664624001839
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author Chun-Yi Lin
Yi-Lun Wu
Yi-Ling Chien
Susan Shur-Fen Gau
author_facet Chun-Yi Lin
Yi-Lun Wu
Yi-Ling Chien
Susan Shur-Fen Gau
author_sort Chun-Yi Lin
collection DOAJ
description Background: Quality of life (QoL) has been suggested as an indicator of outcomes in autistic adults. Factors associated with QoL in autistic individuals remain unclear. This study aims to examine the subjective QoL for autistic adults in Taiwan and investigate the determinants for different domains of QoL. Methods: The study comprised 90 autistic adults (aged 26.9, SD 7.3; males, 80.9%). We used Taiwanese version of World Health Organization Quality of Life-BREF to measure QoL. Four domains of QoL were compared with 61 non-autistic controls, including physical, psychological, social, and environment. To identify the correlates of QoL domains, we assessed IQ, personality trait, family support, anxiety/depressive symptoms, autistic severity, and sensory symptoms by various questionnaires, and assessed their association with QoL by correlation analyses and model selection. Results: Our results showed that autistic adults reported lower QoL on the World Health Organization Quality of Life (WHOQOL)-BREF across all domains. QoL was significantly associated with autistic symptom severity, harm avoidance, family support, sensory symptoms, anxiety, and depression, but not intelligence. Model selections revealed male sex, poor paternal support, autism severity, depression, anxiety, and sensory symptoms were associated with specific QoL domains. Conclusion: Findings supported lower QoL in autistic adults. Modifying the QoL correlates may improve life quality in autistic adults. Furthermore, our findings revealed the importance of sensory symptoms and paternal support in QoL of autistic adults, which was a novel finding in this population.
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spelling doaj-art-dfefd3f328994476b0192fd62d1eb4302025-02-02T05:26:45ZengElsevierJournal of the Formosan Medical Association0929-66462025-02-011242157163Quality of life and clinical correlates in cognitively-able autistic adults: A special focus on sensory characteristics and perceived parental supportChun-Yi Lin0Yi-Lun Wu1Yi-Ling Chien2Susan Shur-Fen Gau3Department of Psychiatry, National Taiwan University Hospital, No.7, Chung-Shan South Road, Taipei, 10002, TaiwanDepartment of Psychiatry, National Taiwan University Hospital, No.7, Chung-Shan South Road, Taipei, 10002, Taiwan; Symphonic Yard Clinic, 2F., Building B, No. 218-2, Section 4, Zhong-Xiao East Road, Taipei, 106059, TaiwanDepartment of Psychiatry, National Taiwan University Hospital, No.7, Chung-Shan South Road, Taipei, 10002, Taiwan; Department of Psychiatry, College of Medicine, National Taiwan University, No.7, Chung-Shan South Road, Taipei, 10002, Taiwan; Corresponding author. Department of Psychiatry, National Taiwan University Hospital and College of Medicine, No.7, Chung-Shan South Road, Taipei, 10002, Taiwan.Department of Psychiatry, National Taiwan University Hospital, No.7, Chung-Shan South Road, Taipei, 10002, Taiwan; Department of Psychiatry, College of Medicine, National Taiwan University, No.7, Chung-Shan South Road, Taipei, 10002, Taiwan; Corresponding author. Department of Psychiatry, National Taiwan University Hospital and College of Medicine, No.7, Chung-Shan South Road, Taipei, 10002, Taiwan.Background: Quality of life (QoL) has been suggested as an indicator of outcomes in autistic adults. Factors associated with QoL in autistic individuals remain unclear. This study aims to examine the subjective QoL for autistic adults in Taiwan and investigate the determinants for different domains of QoL. Methods: The study comprised 90 autistic adults (aged 26.9, SD 7.3; males, 80.9%). We used Taiwanese version of World Health Organization Quality of Life-BREF to measure QoL. Four domains of QoL were compared with 61 non-autistic controls, including physical, psychological, social, and environment. To identify the correlates of QoL domains, we assessed IQ, personality trait, family support, anxiety/depressive symptoms, autistic severity, and sensory symptoms by various questionnaires, and assessed their association with QoL by correlation analyses and model selection. Results: Our results showed that autistic adults reported lower QoL on the World Health Organization Quality of Life (WHOQOL)-BREF across all domains. QoL was significantly associated with autistic symptom severity, harm avoidance, family support, sensory symptoms, anxiety, and depression, but not intelligence. Model selections revealed male sex, poor paternal support, autism severity, depression, anxiety, and sensory symptoms were associated with specific QoL domains. Conclusion: Findings supported lower QoL in autistic adults. Modifying the QoL correlates may improve life quality in autistic adults. Furthermore, our findings revealed the importance of sensory symptoms and paternal support in QoL of autistic adults, which was a novel finding in this population.http://www.sciencedirect.com/science/article/pii/S0929664624001839AdulthoodAutism spectrum disorderQuality of life
spellingShingle Chun-Yi Lin
Yi-Lun Wu
Yi-Ling Chien
Susan Shur-Fen Gau
Quality of life and clinical correlates in cognitively-able autistic adults: A special focus on sensory characteristics and perceived parental support
Journal of the Formosan Medical Association
Adulthood
Autism spectrum disorder
Quality of life
title Quality of life and clinical correlates in cognitively-able autistic adults: A special focus on sensory characteristics and perceived parental support
title_full Quality of life and clinical correlates in cognitively-able autistic adults: A special focus on sensory characteristics and perceived parental support
title_fullStr Quality of life and clinical correlates in cognitively-able autistic adults: A special focus on sensory characteristics and perceived parental support
title_full_unstemmed Quality of life and clinical correlates in cognitively-able autistic adults: A special focus on sensory characteristics and perceived parental support
title_short Quality of life and clinical correlates in cognitively-able autistic adults: A special focus on sensory characteristics and perceived parental support
title_sort quality of life and clinical correlates in cognitively able autistic adults a special focus on sensory characteristics and perceived parental support
topic Adulthood
Autism spectrum disorder
Quality of life
url http://www.sciencedirect.com/science/article/pii/S0929664624001839
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