Modulating tumor-associated macrophages through CSF1R inhibition: a potential therapeutic strategy for HNSCC

Modulating tumor-associated macrophages through CSF1R inhibition: a potential therapeutic strategy for HNSCC

Abstract Purpose Tumor-associated macrophages (TAMs) are pivotal immune cells within the tumor microenvironment (TME), exhibiting dual roles across various cancer types. Depending on the context, TAMs can either suppress tumor progression and weaken drug sensitivity or facilitate tumor growth and dr...

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Bibliographic Details
Main Authors: Kaiting Chen, Xiaochen Li, Shuyi Dong, Yu Guo, Ziyin Luo, Shi-Min Zhuang, Jie Liu, Tianrun Liu, Jing Liao, Weiping Wen
Format: Article
Language:English
Published: BMC 2025-01-01
Series:Journal of Translational Medicine
Subjects:
HNSCC
TAMs
CSF1R inhibitors
Cisplatin
Combination therapy
Online Access:https://doi.org/10.1186/s12967-024-06036-3
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https://doi.org/10.1186/s12967-024-06036-3

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