DEAD‐Box Helicase 6 Blockade in Brain‐Derived Aβ Oligomers From Alzheimer's Disease Patients Attenuates Neurotoxicity

DEAD‐Box Helicase 6 Blockade in Brain‐Derived Aβ Oligomers From Alzheimer's Disease Patients Attenuates Neurotoxicity

ABSTRACT There are no effective curative treatments for Alzheimer's disease (AD), the most prevalent form of dementia. Amyloid‐beta (Aβ) oligomers are considered key neurotoxic molecules that trigger AD. Recent studies have shown that direct antibody targeting of Aβ oligomers is beneficial for...

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Bibliographic Details
Main Authors: Xiaoxu Wang, Lu Dai, Na Wu, Donghui Wu, Xinyuan Wang, Xia Meng, Qilei Zhang, Jing Lu, Xiaoxin Yan, Jing Zhang, Baian Chen
Format: Article
Language:English
Published: Wiley 2025-05-01
Series:MedComm
Subjects:
Aβ oligomers
Alzheimer's disease
DDX6
neurotoxicity
Online Access:https://doi.org/10.1002/mco2.70156
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