Efficacy of Simple Eye Ointment, Polyethylene Cover, and Eyelid Taping in Prevention of Ocular Surface Disorders in Critically Ill Patients: A Randomized Clinical Trial
Background. Under normal conditions, the cornea of the eye is protected from bacterial invasion, physical injury, and drying by the presence of tears, eyelids, and blinking reflex. However, patients admitted to the intensive care unit (ICU) for several reasons including loss of consciousness, receiv...
Saved in:
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2020-01-01
|
| Series: | Critical Care Research and Practice |
| Online Access: | http://dx.doi.org/10.1155/2020/6267432 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832551912296153088 |
|---|---|
| author | Mehdi Ahmadinejad Esmat Karbasi Yunes Jahani Maryam Ahmadipour Maryam Soltaninejad Zahra Karzari |
| author_facet | Mehdi Ahmadinejad Esmat Karbasi Yunes Jahani Maryam Ahmadipour Maryam Soltaninejad Zahra Karzari |
| author_sort | Mehdi Ahmadinejad |
| collection | DOAJ |
| description | Background. Under normal conditions, the cornea of the eye is protected from bacterial invasion, physical injury, and drying by the presence of tears, eyelids, and blinking reflex. However, patients admitted to the intensive care unit (ICU) for several reasons including loss of consciousness, receiving sedative and neuromuscular blocking agents, and mechanical ventilation may lose eye-protective mechanisms causing exposure keratopathy. Therefore, this study intended to compare three eye care methods to prevent ocular surface disorders (OSDs) in ICU patients. Methods. This study was a double-blind clinical trial (IRCT: 201109225426N3, https://www.irct.ir/trial/5825), in which 152 patients were randomized into three groups and each group underwent a different eye care procedure. The eye care methods included simple eye ointment, polyethylene cover, and eyelid taping. The eligible patients received the care procedure for seven days, and their corneas were examined daily for OSD by a portable slit lamp with fluorescein staining. Descriptive and analytical tests (ANOVA, chi-square, logistic regression, and zero-inflated Poisson regression) were used for statistical analysis by STATA14. Results. The odds of OSD (chances of getting an OSD grade between I and VI) in the ointment group were 0.19 (95% CI: 0.09, 0.41), and the odds of OSD in the polyethylene cover group were 0.06 (95% CI: 0.01, 0.20), showing a significant difference with the tape group (p=0.0001). Despite the lower odds of OSD in the cover group than in the ointment group, there was no significant between-group difference (p=0.08). However, the mean OSD scores in both the ointment and polyethylene cover groups were significantly lower than that in the tape group. Conclusion. The results of this study showed that polyethylene cover followed by simple eye ointment and eyelid taping were the most effective methods in preventing OSD. Therefore, polyethylene cover and simple eye ointment are recommended as effective eye care methods in ICU. |
| format | Article |
| id | doaj-art-df9f6cb116ef4a24a366028ba6bd9be2 |
| institution | Kabale University |
| issn | 2090-1305 2090-1313 |
| language | English |
| publishDate | 2020-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Critical Care Research and Practice |
| spelling | doaj-art-df9f6cb116ef4a24a366028ba6bd9be22025-02-03T06:00:11ZengWileyCritical Care Research and Practice2090-13052090-13132020-01-01202010.1155/2020/62674326267432Efficacy of Simple Eye Ointment, Polyethylene Cover, and Eyelid Taping in Prevention of Ocular Surface Disorders in Critically Ill Patients: A Randomized Clinical TrialMehdi Ahmadinejad0Esmat Karbasi1Yunes Jahani2Maryam Ahmadipour3Maryam Soltaninejad4Zahra Karzari5Department of Anesthesiology, Faculty of Medicine, Kerman University of Medical Sciences, Kerman, IranDepartment of Ophthalmology, Faculty of Medicine, Kerman University of Medical Sciences, Kerman, IranModeling in Health Research Center, Institute for Futures Studies in Health, Kerman University of Medical Sciences, Kerman, IranDepartment of Pediatrics, Faculty of Medicine, Kerman University of Medical Sciences, Kerman, IranCritical Care Nurse, Kerman University of Medical Sciences, Kerman, IranDepartment of Nursing, Midwifery and Health, Faculty of Nursing, Kerman Branch, Islamic Azad University, Kerman, IranBackground. Under normal conditions, the cornea of the eye is protected from bacterial invasion, physical injury, and drying by the presence of tears, eyelids, and blinking reflex. However, patients admitted to the intensive care unit (ICU) for several reasons including loss of consciousness, receiving sedative and neuromuscular blocking agents, and mechanical ventilation may lose eye-protective mechanisms causing exposure keratopathy. Therefore, this study intended to compare three eye care methods to prevent ocular surface disorders (OSDs) in ICU patients. Methods. This study was a double-blind clinical trial (IRCT: 201109225426N3, https://www.irct.ir/trial/5825), in which 152 patients were randomized into three groups and each group underwent a different eye care procedure. The eye care methods included simple eye ointment, polyethylene cover, and eyelid taping. The eligible patients received the care procedure for seven days, and their corneas were examined daily for OSD by a portable slit lamp with fluorescein staining. Descriptive and analytical tests (ANOVA, chi-square, logistic regression, and zero-inflated Poisson regression) were used for statistical analysis by STATA14. Results. The odds of OSD (chances of getting an OSD grade between I and VI) in the ointment group were 0.19 (95% CI: 0.09, 0.41), and the odds of OSD in the polyethylene cover group were 0.06 (95% CI: 0.01, 0.20), showing a significant difference with the tape group (p=0.0001). Despite the lower odds of OSD in the cover group than in the ointment group, there was no significant between-group difference (p=0.08). However, the mean OSD scores in both the ointment and polyethylene cover groups were significantly lower than that in the tape group. Conclusion. The results of this study showed that polyethylene cover followed by simple eye ointment and eyelid taping were the most effective methods in preventing OSD. Therefore, polyethylene cover and simple eye ointment are recommended as effective eye care methods in ICU.http://dx.doi.org/10.1155/2020/6267432 |
| spellingShingle | Mehdi Ahmadinejad Esmat Karbasi Yunes Jahani Maryam Ahmadipour Maryam Soltaninejad Zahra Karzari Efficacy of Simple Eye Ointment, Polyethylene Cover, and Eyelid Taping in Prevention of Ocular Surface Disorders in Critically Ill Patients: A Randomized Clinical Trial Critical Care Research and Practice |
| title | Efficacy of Simple Eye Ointment, Polyethylene Cover, and Eyelid Taping in Prevention of Ocular Surface Disorders in Critically Ill Patients: A Randomized Clinical Trial |
| title_full | Efficacy of Simple Eye Ointment, Polyethylene Cover, and Eyelid Taping in Prevention of Ocular Surface Disorders in Critically Ill Patients: A Randomized Clinical Trial |
| title_fullStr | Efficacy of Simple Eye Ointment, Polyethylene Cover, and Eyelid Taping in Prevention of Ocular Surface Disorders in Critically Ill Patients: A Randomized Clinical Trial |
| title_full_unstemmed | Efficacy of Simple Eye Ointment, Polyethylene Cover, and Eyelid Taping in Prevention of Ocular Surface Disorders in Critically Ill Patients: A Randomized Clinical Trial |
| title_short | Efficacy of Simple Eye Ointment, Polyethylene Cover, and Eyelid Taping in Prevention of Ocular Surface Disorders in Critically Ill Patients: A Randomized Clinical Trial |
| title_sort | efficacy of simple eye ointment polyethylene cover and eyelid taping in prevention of ocular surface disorders in critically ill patients a randomized clinical trial |
| url | http://dx.doi.org/10.1155/2020/6267432 |
| work_keys_str_mv | AT mehdiahmadinejad efficacyofsimpleeyeointmentpolyethylenecoverandeyelidtapinginpreventionofocularsurfacedisordersincriticallyillpatientsarandomizedclinicaltrial AT esmatkarbasi efficacyofsimpleeyeointmentpolyethylenecoverandeyelidtapinginpreventionofocularsurfacedisordersincriticallyillpatientsarandomizedclinicaltrial AT yunesjahani efficacyofsimpleeyeointmentpolyethylenecoverandeyelidtapinginpreventionofocularsurfacedisordersincriticallyillpatientsarandomizedclinicaltrial AT maryamahmadipour efficacyofsimpleeyeointmentpolyethylenecoverandeyelidtapinginpreventionofocularsurfacedisordersincriticallyillpatientsarandomizedclinicaltrial AT maryamsoltaninejad efficacyofsimpleeyeointmentpolyethylenecoverandeyelidtapinginpreventionofocularsurfacedisordersincriticallyillpatientsarandomizedclinicaltrial AT zahrakarzari efficacyofsimpleeyeointmentpolyethylenecoverandeyelidtapinginpreventionofocularsurfacedisordersincriticallyillpatientsarandomizedclinicaltrial |