Socioeconomic status and delayed surgery: impact on non-metastatic papillary thyroid carcinoma outcomes
IntroductionThe growing popularity of active surveillance for papillary thyroid cancer and the COVID-19 pandemic have increased surgery delay, further necessitating a reassessment of the link between surgery delay and survival outcomes for papillary thyroid cancer. In this study, we aim to investiga...
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Frontiers Media S.A.
2025-01-01
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fpubh.2024.1488294/full |
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| author | Kun Zhang Xinyi Wang Jianyong Lei Anping Su Tao Wei Zhihui Li Ya-Wen Chen Ya-Wen Chen Ya-Wen Chen Ya-Wen Chen Ya-Wen Chen |
| author_facet | Kun Zhang Xinyi Wang Jianyong Lei Anping Su Tao Wei Zhihui Li Ya-Wen Chen Ya-Wen Chen Ya-Wen Chen Ya-Wen Chen Ya-Wen Chen |
| author_sort | Kun Zhang |
| collection | DOAJ |
| description | IntroductionThe growing popularity of active surveillance for papillary thyroid cancer and the COVID-19 pandemic have increased surgery delay, further necessitating a reassessment of the link between surgery delay and survival outcomes for papillary thyroid cancer. In this study, we aim to investigate the interplay among various oncological factors, socioeconomic status, and surgical timing with respect to survival outcomes of papillary thyroid cancer.MethodsA total of 58,378 non-metastatic papillary thyroid cancer patients from 2000 to 2018 were screened from the Surveillance, Epidemiology, and End Results database. Kaplan–Meier survival curve, Cox proportional hazard regression, competing risk hazard regression, and multinomial logistic regression were applied.ResultsReceiving neck dissection or radioactive iodine therapy, being married at diagnosis, living in an urban area, being richer, and being of other minority ethnicity were estimated to be independent predictors for better overall survival. Single, older Black patients living in rural areas that experienced long surgery delays were more associated with a higher non- papillary thyroid cancer mortality rate. High income level was the only independent socioeconomic status predictor for lower papillary thyroid cancer -specific mortality. Unmarried, older patients of minority ethnicity tended to undergo longer surgery delays.ConclusionSurgery for non-metastatic papillary thyroid cancer patients can be safely delayed. The elevated non-papillary thyroid cancer mortality has reflected low socioeconomic status population’s survival status. |
| format | Article |
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| institution | Kabale University |
| issn | 2296-2565 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Frontiers Media S.A. |
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| series | Frontiers in Public Health |
| spelling | doaj-art-df958a2916c24ad88d2fc59451f723f92025-01-22T07:11:14ZengFrontiers Media S.A.Frontiers in Public Health2296-25652025-01-011210.3389/fpubh.2024.14882941488294Socioeconomic status and delayed surgery: impact on non-metastatic papillary thyroid carcinoma outcomesKun Zhang0Xinyi Wang1Jianyong Lei2Anping Su3Tao Wei4Zhihui Li5Ya-Wen Chen6Ya-Wen Chen7Ya-Wen Chen8Ya-Wen Chen9Ya-Wen Chen10Division of Thyroid Surgery, Department of General Surgery, West China Hospital, Sichuan University, Chengdu, Sichuan, ChinaDivision of Thyroid Surgery, Department of General Surgery, West China Hospital, Sichuan University, Chengdu, Sichuan, ChinaDivision of Thyroid Surgery, Department of General Surgery, West China Hospital, Sichuan University, Chengdu, Sichuan, ChinaDivision of Thyroid Surgery, Department of General Surgery, West China Hospital, Sichuan University, Chengdu, Sichuan, ChinaDivision of Thyroid Surgery, Department of General Surgery, West China Hospital, Sichuan University, Chengdu, Sichuan, ChinaDivision of Thyroid Surgery, Department of General Surgery, West China Hospital, Sichuan University, Chengdu, Sichuan, ChinaDepartment of Otolaryngology, Icahn School of Medicine at Mount Sinai, New York, NY, United StatesDepartment of Cell, Developmental, and Regenerative Biology, Icahn School of Medicine at Mount Sinai, New York, NY, United StatesBlack Family Stem Cell Institute, Icahn School of Medicine at Mount Sinai, New York, NY, United StatesInstitute for Airway Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, United StatesCenter for Epithelial and Airway Biology and Regeneration, Icahn School of Medicine at Mount Sinai, New York, NY, United StatesIntroductionThe growing popularity of active surveillance for papillary thyroid cancer and the COVID-19 pandemic have increased surgery delay, further necessitating a reassessment of the link between surgery delay and survival outcomes for papillary thyroid cancer. In this study, we aim to investigate the interplay among various oncological factors, socioeconomic status, and surgical timing with respect to survival outcomes of papillary thyroid cancer.MethodsA total of 58,378 non-metastatic papillary thyroid cancer patients from 2000 to 2018 were screened from the Surveillance, Epidemiology, and End Results database. Kaplan–Meier survival curve, Cox proportional hazard regression, competing risk hazard regression, and multinomial logistic regression were applied.ResultsReceiving neck dissection or radioactive iodine therapy, being married at diagnosis, living in an urban area, being richer, and being of other minority ethnicity were estimated to be independent predictors for better overall survival. Single, older Black patients living in rural areas that experienced long surgery delays were more associated with a higher non- papillary thyroid cancer mortality rate. High income level was the only independent socioeconomic status predictor for lower papillary thyroid cancer -specific mortality. Unmarried, older patients of minority ethnicity tended to undergo longer surgery delays.ConclusionSurgery for non-metastatic papillary thyroid cancer patients can be safely delayed. The elevated non-papillary thyroid cancer mortality has reflected low socioeconomic status population’s survival status.https://www.frontiersin.org/articles/10.3389/fpubh.2024.1488294/fulloverall survivalprognostic factorspapillary thyroid cancersocioeconomic statussurgery delay |
| spellingShingle | Kun Zhang Xinyi Wang Jianyong Lei Anping Su Tao Wei Zhihui Li Ya-Wen Chen Ya-Wen Chen Ya-Wen Chen Ya-Wen Chen Ya-Wen Chen Socioeconomic status and delayed surgery: impact on non-metastatic papillary thyroid carcinoma outcomes Frontiers in Public Health overall survival prognostic factors papillary thyroid cancer socioeconomic status surgery delay |
| title | Socioeconomic status and delayed surgery: impact on non-metastatic papillary thyroid carcinoma outcomes |
| title_full | Socioeconomic status and delayed surgery: impact on non-metastatic papillary thyroid carcinoma outcomes |
| title_fullStr | Socioeconomic status and delayed surgery: impact on non-metastatic papillary thyroid carcinoma outcomes |
| title_full_unstemmed | Socioeconomic status and delayed surgery: impact on non-metastatic papillary thyroid carcinoma outcomes |
| title_short | Socioeconomic status and delayed surgery: impact on non-metastatic papillary thyroid carcinoma outcomes |
| title_sort | socioeconomic status and delayed surgery impact on non metastatic papillary thyroid carcinoma outcomes |
| topic | overall survival prognostic factors papillary thyroid cancer socioeconomic status surgery delay |
| url | https://www.frontiersin.org/articles/10.3389/fpubh.2024.1488294/full |
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