Recurrent Postoperative Spinal Epidural Hematoma in a Patient with Protein S Deficiency
A 71-year-old man underwent cervical laminectomy and developed two symptomatic epidural hematomas during the acute postoperative period. On both occasions, drain obstruction was the predominant cause. Congenital Protein S deficiency was diagnosed postoperatively. Protein S is a vitamin K-dependent n...
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| Format: | Article |
| Language: | English |
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Wiley
2015-01-01
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| Series: | Case Reports in Orthopedics |
| Online Access: | http://dx.doi.org/10.1155/2015/536592 |
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| _version_ | 1832552885113585664 |
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| author | Masato Anno Takashi Yamazaki Nobuhiro Hara Keishi Hayakawa |
| author_facet | Masato Anno Takashi Yamazaki Nobuhiro Hara Keishi Hayakawa |
| author_sort | Masato Anno |
| collection | DOAJ |
| description | A 71-year-old man underwent cervical laminectomy and developed two symptomatic epidural hematomas during the acute postoperative period. On both occasions, drain obstruction was the predominant cause. Congenital Protein S deficiency was diagnosed postoperatively. Protein S is a vitamin K-dependent natural anticoagulant and is essential for inhibiting thrombosis in microcirculation. We assume that Protein S deficiency followed by perioperative bed-rest and surgical invasiveness led to severe hypercoagulability and subsequent drain obstruction. The present findings suggest that both bleeding disorders and hypercoagulability are risk factors for postoperative symptomatic epidural hematoma. |
| format | Article |
| id | doaj-art-df803cb966ef45c6af4ee9f0ce033218 |
| institution | Kabale University |
| issn | 2090-6749 2090-6757 |
| language | English |
| publishDate | 2015-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Orthopedics |
| spelling | doaj-art-df803cb966ef45c6af4ee9f0ce0332182025-02-03T05:57:36ZengWileyCase Reports in Orthopedics2090-67492090-67572015-01-01201510.1155/2015/536592536592Recurrent Postoperative Spinal Epidural Hematoma in a Patient with Protein S DeficiencyMasato Anno0Takashi Yamazaki1Nobuhiro Hara2Keishi Hayakawa3Department of Orthopaedic Surgery, Musashino Red Cross Hospital, 1-26-1 Kyonan-cho, Musashino-shi, Tokyo 1800023, JapanDepartment of Orthopaedic Surgery, Musashino Red Cross Hospital, 1-26-1 Kyonan-cho, Musashino-shi, Tokyo 1800023, JapanDepartment of Orthopaedic Surgery, Musashino Red Cross Hospital, 1-26-1 Kyonan-cho, Musashino-shi, Tokyo 1800023, JapanDepartment of Orthopaedic Surgery, Musashino Red Cross Hospital, 1-26-1 Kyonan-cho, Musashino-shi, Tokyo 1800023, JapanA 71-year-old man underwent cervical laminectomy and developed two symptomatic epidural hematomas during the acute postoperative period. On both occasions, drain obstruction was the predominant cause. Congenital Protein S deficiency was diagnosed postoperatively. Protein S is a vitamin K-dependent natural anticoagulant and is essential for inhibiting thrombosis in microcirculation. We assume that Protein S deficiency followed by perioperative bed-rest and surgical invasiveness led to severe hypercoagulability and subsequent drain obstruction. The present findings suggest that both bleeding disorders and hypercoagulability are risk factors for postoperative symptomatic epidural hematoma.http://dx.doi.org/10.1155/2015/536592 |
| spellingShingle | Masato Anno Takashi Yamazaki Nobuhiro Hara Keishi Hayakawa Recurrent Postoperative Spinal Epidural Hematoma in a Patient with Protein S Deficiency Case Reports in Orthopedics |
| title | Recurrent Postoperative Spinal Epidural Hematoma in a Patient with Protein S Deficiency |
| title_full | Recurrent Postoperative Spinal Epidural Hematoma in a Patient with Protein S Deficiency |
| title_fullStr | Recurrent Postoperative Spinal Epidural Hematoma in a Patient with Protein S Deficiency |
| title_full_unstemmed | Recurrent Postoperative Spinal Epidural Hematoma in a Patient with Protein S Deficiency |
| title_short | Recurrent Postoperative Spinal Epidural Hematoma in a Patient with Protein S Deficiency |
| title_sort | recurrent postoperative spinal epidural hematoma in a patient with protein s deficiency |
| url | http://dx.doi.org/10.1155/2015/536592 |
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