Multiplex qPCR discriminates variants of concern to enhance global surveillance of SARS-CoV-2.

Multiplex qPCR discriminates variants of concern to enhance global surveillance of SARS-CoV-2.

With the emergence of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) variants that may increase transmissibility and/or cause escape from immune responses, there is an urgent need for the targeted surveillance of circulating lineages. It was found that the B.1.1.7 (also 501Y.V1) varian...

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Main Authors: Chantal B F Vogels, Mallery I Breban, Isabel M Ott, Tara Alpert, Mary E Petrone, Anne E Watkins, Chaney C Kalinich, Rebecca Earnest, Jessica E Rothman, Jaqueline Goes de Jesus, Ingra Morales Claro, Giulia Magalhães Ferreira, Myuki A E Crispim, Brazil-UK CADDE Genomic Network, Lavanya Singh, Houriiyah Tegally, Ugochukwu J Anyaneji, Network for Genomic Surveillance in South Africa, Emma B Hodcroft, Christopher E Mason, Gaurav Khullar, Jessica Metti, Joel T Dudley, Matthew J MacKay, Megan Nash, Jianhui Wang, Chen Liu, Pei Hui, Steven Murphy, Caleb Neal, Eva Laszlo, Marie L Landry, Anthony Muyombwe, Randy Downing, Jafar Razeq, Tulio de Oliveira, Nuno R Faria, Ester C Sabino, Richard A Neher, Joseph R Fauver, Nathan D Grubaugh
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-05-01
Series:PLoS Biology
Online Access:https://doi.org/10.1371/journal.pbio.3001236
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