Optimising (re-)irradiation for locally recurrent head and neck cancer: impact of dose-escalation, salvage surgery, PEG tube and biomarkers on oncological outcomes—a single centre analysis

Optimising (re-)irradiation for locally recurrent head and neck cancer: impact of dose-escalation, salvage surgery, PEG tube and biomarkers on oncological outcomes—a single centre analysis

Abstract Introduction Locoregional recurrence (LR) is common in locally advanced head and neck cancer (HNSCC), posing challenges for treatment. We analysed outcome parameters and toxicities for patients being treated with radiotherapy (RT) for LR-HNSCC and investigated patient and disease related pr...

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Main Authors: Julia Katharina Schleifenbaum, Janis Morgenthaler, Shachi Jenny Sharma, Jens Peter Klußmann, Philipp Linde, Simone Wegen, Johannes Rosenbrock, Christian Baues, Emmanouil Fokas, Richard Khor, Sweet Ping Ng, Simone Marnitz, Maike Trommer
Format: Article
Language:English
Published: BMC 2025-01-01
Series:Radiation Oncology
Subjects:
Recurrent head and neck cancer
Reirradiation
Salvage therapy
PEG tube
Inflammation
Biomarkers
Online Access:https://doi.org/10.1186/s13014-024-02570-y
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https://doi.org/10.1186/s13014-024-02570-y

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