Recent Innovations in Retinal Laser Therapy

The early history of retinal laser therapy began with the observation of solar blindness, leading to the development of various laser technologies for treating retinal diseases. The first retinal photocoagulation machine was developed in 1956, and subsequent advancements introduced ruby and argon la...

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Main Authors: Mi Zheng, Yannis M. Paulus
Format: Article
Language:English
Published: MDPI AG 2025-02-01
Series:Photonics
Subjects:
Online Access:https://www.mdpi.com/2304-6732/12/2/156
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author Mi Zheng
Yannis M. Paulus
author_facet Mi Zheng
Yannis M. Paulus
author_sort Mi Zheng
collection DOAJ
description The early history of retinal laser therapy began with the observation of solar blindness, leading to the development of various laser technologies for treating retinal diseases. The first retinal photocoagulation machine was developed in 1956, and subsequent advancements introduced ruby and argon lasers. While conventional theories posited that retinal damage was an indispensable prerequisite for therapeutic effects, emergent insights highlight the non-damaging mechanisms, such as photostimulation- and self-repair-related mechanisms. Novel therapies, such as subthreshold micropulse laser (SMPL) and selective retina therapy (SRT), are now being employed alongside innovative delivery systems to improve treatment efficiency and safety. Clinical studies are underway to evaluate the efficacy of these therapies for conditions like diabetic retinopathy and central serous chorioretinopathy. Despite the challenges in standardization and long-term evaluation, these innovations represent significant progress towards safer and more effective laser treatment for retinal diseases.
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spelling doaj-art-df5a454b88ff4be182a93dba3f7f40b82025-08-20T02:44:32ZengMDPI AGPhotonics2304-67322025-02-0112215610.3390/photonics12020156Recent Innovations in Retinal Laser TherapyMi Zheng0Yannis M. Paulus1Department of Ophthalmology, Wilmer Eye Institute, Johns Hopkins University, Baltimore, MD 21287, USADepartment of Ophthalmology, Wilmer Eye Institute, Johns Hopkins University, Baltimore, MD 21287, USAThe early history of retinal laser therapy began with the observation of solar blindness, leading to the development of various laser technologies for treating retinal diseases. The first retinal photocoagulation machine was developed in 1956, and subsequent advancements introduced ruby and argon lasers. While conventional theories posited that retinal damage was an indispensable prerequisite for therapeutic effects, emergent insights highlight the non-damaging mechanisms, such as photostimulation- and self-repair-related mechanisms. Novel therapies, such as subthreshold micropulse laser (SMPL) and selective retina therapy (SRT), are now being employed alongside innovative delivery systems to improve treatment efficiency and safety. Clinical studies are underway to evaluate the efficacy of these therapies for conditions like diabetic retinopathy and central serous chorioretinopathy. Despite the challenges in standardization and long-term evaluation, these innovations represent significant progress towards safer and more effective laser treatment for retinal diseases.https://www.mdpi.com/2304-6732/12/2/156retinal lasersubthreshold micropulse laserpattern scanning laserPASCALselective retina therapyendpoint management
spellingShingle Mi Zheng
Yannis M. Paulus
Recent Innovations in Retinal Laser Therapy
Photonics
retinal laser
subthreshold micropulse laser
pattern scanning laser
PASCAL
selective retina therapy
endpoint management
title Recent Innovations in Retinal Laser Therapy
title_full Recent Innovations in Retinal Laser Therapy
title_fullStr Recent Innovations in Retinal Laser Therapy
title_full_unstemmed Recent Innovations in Retinal Laser Therapy
title_short Recent Innovations in Retinal Laser Therapy
title_sort recent innovations in retinal laser therapy
topic retinal laser
subthreshold micropulse laser
pattern scanning laser
PASCAL
selective retina therapy
endpoint management
url https://www.mdpi.com/2304-6732/12/2/156
work_keys_str_mv AT mizheng recentinnovationsinretinallasertherapy
AT yannismpaulus recentinnovationsinretinallasertherapy