Targeted Inhibition of CHD1L by OTI-611 Reprograms Chemotherapy and Targeted Therapy-Induced Cell Cycle Arrest and Suppresses Proliferation to Produce Synergistic Antitumor Effects in Breast and Colorectal Cancer

The second and third most frequently diagnosed cancers worldwide are breast (2.3 million new cases) and colorectal (1.9 million new cases), respectively. Although advances in cancer therapies and early detection have improved the overall survival of patients, patients still develop resistance or can...

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Bibliographic Details
Main Authors: Hector Esquer, Qiong Zhou, Daniel V. LaBarbera
Format: Article
Language:English
Published: MDPI AG 2025-02-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/14/5/318
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