Integrative Proteomic and Phosphoproteomic Profiling Reveals Molecular Mechanisms of Hypoxic Adaptation in Brandt’s Voles (<i>Lasiopodomys brandtii</i>) Brain Tissue

Integrative Proteomic and Phosphoproteomic Profiling Reveals Molecular Mechanisms of Hypoxic Adaptation in Brandt’s Voles (<i>Lasiopodomys brandtii</i>) Brain Tissue

Rapid ascent to high altitudes by unacclimatized individuals significantly increases the risk of brain damage, given the brain’s heightened sensitivity to hypoxic conditions. Investigating hypoxia-tolerant animals can provide insights into adaptive mechanisms and guide prevention and treatment of hy...

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Bibliographic Details
Main Authors: Panqin Wang, Yongyan Liu, Yimeng Du, Yiwen Gao, Tian Shao, Weifeng Guo, Zhenlong Wang, Han Cheng
Format: Article
Language:English
Published: MDPI AG 2025-04-01
Series:Cells
Subjects:
Brandt’s voles
brain
hypoxia
proteomic
phosphoproteomic
Online Access:https://www.mdpi.com/2073-4409/14/7/527
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