miR-125b differentially impacts mineralization in dexamethasone and calcium-treated human mesenchymal stem cells

miR-125b differentially impacts mineralization in dexamethasone and calcium-treated human mesenchymal stem cells

Bone metabolism is highly regulated, and microRNAs (miRs) can contribute to this process. Among them, miR-125b is well known to enhance osteoporosis and reduce osteogenic differentiation of human mesenchymal stem cells (hMSCs). In this work, we aim to evaluate and understand how miR-125b modulates m...

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Bibliographic Details
Main Authors: Virginie Joris, Elizabeth R. Balmayor, Martijn van Griensven
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:Molecular Therapy: Nucleic Acids
Subjects:
MT: Non-coding RNAs
dexamethasone
calcium
miR-125b
mineralization
molecular mechanisms
Online Access:http://www.sciencedirect.com/science/article/pii/S2162253124003330
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