Hydrogen gas inhalation ameliorates glomerular enlargement after hypoxic-ischemic insult in asphyxiated piglet model

Hydrogen gas inhalation ameliorates glomerular enlargement after hypoxic-ischemic insult in asphyxiated piglet model

Abstract Acute kidney injury (AKI) has been reported to occur in 30–70% of asphyxiated neonates. Hydrogen (H2) gas became a major research focus in neonatal medicine after the identification of its robust antioxidative properties. However, the ability of H2 gas to ameliorate AKI is unknown. We exami...

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Main Authors: Takuma Iwaki, Shinji Nakamura, Takayuki Wakabayashi, Yasuhiro Nakao, Yinmon Htun, Toui Tsuchiya, Tsutomu Mitsuie, Kosuke Koyano, Aya Morimoto, Noriko Fuke, Takayuki Yokota, Sonoko Kondo, Yukihiko Konishi, Takanori Miki, Masaki Ueno, Takashi Iwase, Takashi Kusaka
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Scientific Reports
Subjects:
Acute kidney injury
Asphyxia
Glomerular enlargement
Hydrogen gas
Hypoxic-ischemia
Piglet
Online Access:https://doi.org/10.1038/s41598-025-85231-8
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https://doi.org/10.1038/s41598-025-85231-8

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