Saliva, Plasma, and Multifluid Metabolomic Signatures of Periodontal Disease, Type 2 Diabetes Progression, and Markers of Glycemia and Dyslipidemia Among Puerto Rican Adults With Overweight and Obesity

Saliva, Plasma, and Multifluid Metabolomic Signatures of Periodontal Disease, Type 2 Diabetes Progression, and Markers of Glycemia and Dyslipidemia Among Puerto Rican Adults With Overweight and Obesity

Background Evidence from cohort studies indicates a bidirectional relationship between periodontal disease and type 2 diabetes (T2D), but the underlying mechanisms remain unknown. In this study, we aimed to (1) identify saliva, plasma, and multifluid metabolomic signatures associated with periodonta...

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Main Authors: Zicheng Wang, Danielle E. Haslam, Caleigh M. Sawicki, Sona Rivas‐Tumanyan, Frank B. Hu, Liming Liang, David T. W. Wong, Kaumudi J. Joshipura, Shilpa N. Bhupathiraju
Format: Article
Language:English
Published: Wiley 2024-08-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
metabolomics
periodontal disease
plasma metabolites
saliva metabolites
T2D progression
type 2 diabetes
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.123.033350
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https://www.ahajournals.org/doi/10.1161/JAHA.123.033350

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