Design of a Glycoconjugate Vaccine Against <i>Salmonella</i> Paratyphi A

Design of a Glycoconjugate Vaccine Against <i>Salmonella</i> Paratyphi A

Background/Objectives: Typhoid and paratyphoid fever together are responsible for millions of cases and thousands of deaths per year, most of which occur in children in South and Southeast Asia. While typhoid conjugate vaccines (TCVs) are licensed, no vaccines are currently available against <i&g...

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Bibliographic Details
Main Authors: Renzo Alfini, Martina Carducci, Luisa Massai, Daniele De Simone, Marco Mariti, Omar Rossi, Simona Rondini, Francesca Micoli, Carlo Giannelli
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Vaccines
Subjects:
<i>Salmonella</i> Paratyphi A
critical quality attribute (CQA)
O-antigen (O:2)
conjugate
1-cyano-4-dimethylaminopyridine tetrafluoroborate (CDAP)
immunogenicity
Online Access:https://www.mdpi.com/2076-393X/12/11/1272
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