Effect of anti-CD4 mAb induced by inhibiting B cell disorder on immune reconstruction of HIV-infected immunological non-responders

Abstract Background In persons living with HIV, antiretroviral therapy (ART) reduces HIV RNA in their plasma and increases CD4 + T lymphocytes, thus restoring their immune function and reducing mortality rates. Methods The heavy and light chains of B cell receptor (BCR) were amplified, sequenced, an...

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Bibliographic Details
Main Authors: Yi Ouyang, Kang Wu, Lei Fu, Panpan Yi, Da Cheng, Xiaoyu Fu
Format: Article
Language:English
Published: BMC 2025-06-01
Series:Molecular Medicine
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Online Access:https://doi.org/10.1186/s10020-025-01286-3
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