Identifying promising peptide targets for leprosy serological tests: From prediction to ELISA

Identifying promising peptide targets for leprosy serological tests: From prediction to ELISA

Leprosy remains a significant health concern, particularly in India, Brazil, and Indonesia. Early diagnosis is essential to prevent complications, highlighting the need for improved diagnostic tools. This study aimed to identify novel Mycobacterium leprae antigens and assess their effectiveness agai...

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Main Authors: Augusto César Parreiras de Jesus, Vanêssa Gomes Fraga, Samuel Alexandre Pimenta-Carvalho, Tania Mara Pinto Dabés Guimarães, Marcio Sobreira Silva Araújo, Jairo Campos de Carvalho, Marcio Bezerra Santos, Marcelo Grossi Araújo, Marcelo Antonio Pascoal-Xavier, Sandra Lyon, Sebastião Rodrigo Ferreira, Rocio Arreguin-Campos, Kasper Eersels, Bart van Grinsven, Thomas Cleij, Lilian Lacerda Bueno, Daniella Castanheira Bartholomeu, Cristiane Alves da Silva Menezes, Ana Laura Grossi de Oliveira, Ricardo Toshio Fujiwara
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:Journal of Genetic Engineering and Biotechnology
Subjects:
Leprosy
Serology
Peptides
Bioinformatics
Diagnostics
Online Access:http://www.sciencedirect.com/science/article/pii/S1687157X25000198
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