Overview of Roles of Novel Components in the Regulation of DNA Damage Repair in BRCA1-Deficient Cancers: An Update
Cancers that arise from germline mutations of breast cancer associated gene 1 (<i>BRCA1</i>), which is a crucial player in homologous recombination (HR) DNA repair, are vulnerable to DNA-damaging agents such as platinum and PARP inhibitors (PARPis). Increasing evidence suggests that BRCA...
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| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2025-04-01
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| Series: | DNA |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2673-8856/5/2/17 |
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