Lineage-specific microbial protein prediction enables large-scale exploration of protein ecology within the human gut

Abstract Microbes use a range of genetic codes and gene structures, yet these are often ignored during metagenomic analysis. This causes spurious protein predictions, preventing functional assignment which limits our understanding of ecosystems. To resolve this, we developed a lineage-specific gene...

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Bibliographic Details
Main Authors: Matthias A. Schmitz, Nicholas J. Dimonaco, Thomas Clavel, Thomas C. A. Hitch
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-58442-w
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