SARS-CoV-2 antibody responses in children exhibit higher FcR engagement and avidity than in adults

SARS-CoV-2 antibody responses in children exhibit higher FcR engagement and avidity than in adults

Abstract As intrinsic differences in humoral immune response to SARS-CoV-2 between children and adults remain unclear, we improved characterisation by defining the kinetics, specificity and function of antibodies to SARS-CoV-2 in children (n = 146, aged 9.4 ± 4.8 years with n = 257 samples) compared...

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Main Authors: Carolyn A. Cohen, Ludivine Grzelak, Susan S. Chiu, David SC Hui, Mike YW Kwan, Owen TY Tsang, Wai Hung Chan, Yat Sun Yau, Kelly WK Lee, Masashi Mori, Gaya K. Amarasinghe, Samuel MS Cheng, Leo LM Poon, Malik Peiris, Sophie A. Valkenburg
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-63263-y
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https://doi.org/10.1038/s41467-025-63263-y

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