Near-native state imaging by cryo-soft-X-ray tomography reveals remodelling of multiple cellular organelles during HSV-1 infection.

Herpes simplex virus-1 (HSV-1) is a large, enveloped DNA virus and its assembly in the cell is a complex multi-step process during which viral particles interact with numerous cellular compartments such as the nucleus and organelles of the secretory pathway. Transmission electron microscopy and fluo...

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Bibliographic Details
Main Authors: Kamal L Nahas, Viv Connor, Katharina M Scherer, Clemens F Kaminski, Maria Harkiolaki, Colin M Crump, Stephen C Graham
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-07-01
Series:PLoS Pathogens
Online Access:https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1010629&type=printable
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