Altuvoct: Innovative Medicinal Products Benefit from Innovative Approaches to Regulatory Assessment

Efanesoctocog alfa (Altuvoct; BIVV001) is a fusion protein comprising domains of (i) factor VIII, (ii) the von Willebrand factor, and (iii) IgG1 coupled to two polypeptide linkers. The half-life of efanesoctocog alfa in plasma is about 40 h. The polypeptide linkers are released by thrombin activatio...

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Bibliographic Details
Main Authors: Essam Kerwash, Maria Malamatari, John D. Johnston
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Life
Subjects:
Online Access:https://www.mdpi.com/2075-1729/15/6/848
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