Repurposing Copper(II)/THPTA as A Bioorthogonal Catalyst for Thiazolidine Bond Cleavage

Repurposing Copper(II)/THPTA as A Bioorthogonal Catalyst for Thiazolidine Bond Cleavage

Abstract Metal‐mediated chemical transformations are promising approaches to manipulate and regulate proteins in fundamental biological research and therapeutic development. Nevertheless, unlike bond‐forming reactions, the exploration of selective bond cleavage reactions catalyzed by metals that are...

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Bibliographic Details
Main Authors: Chengyun Ma, Guoqing Liu, Juan Yin, Jianan Sun, Disheng Luo, Dechun Yang, Shuo Pang, Wei Hou, Xinya Hemu, Bangce Ye, Xiaobao Bi
Format: Article
Language:English
Published: Wiley 2024-11-01
Series:Advanced Science
Subjects:
bioorthogonal catalysts
bond cleavage reactions
copper ions
living systems
metals
thiazolidines
Online Access:https://doi.org/10.1002/advs.202408180
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