A novel calreticulin of Psoroptes ovis regulated keratinocyte function resulting in host skin barrier dysfunction: implications for involvement in the pathogenesis of psoroptic mange

A novel calreticulin of Psoroptes ovis regulated keratinocyte function resulting in host skin barrier dysfunction: implications for involvement in the pathogenesis of psoroptic mange

Abstract Background Psoroptes ovis, the causative agent of psoroptic mange, affects a wide range of domestic and wild animals, causing substantial economic losses and threatening wildlife survival. However, the underlying pathogenesis of this ectoparasitic disease remains poorly understood. Methods...

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Bibliographic Details
Main Authors: Yane Li, Guiying Hao, Je Fan, Fangyan Wu, Xiangyue Yao, Youping Liang, Jing Xu, Ran He, Hui Wang, Yue Xie, Xiaobin Gu
Format: Article
Language:English
Published: BMC 2025-05-01
Series:Parasites & Vectors
Subjects:
Psoroptes ovis
Calreticulin
Tissue localization
Keratinocytes
Immune regulation
Online Access:https://doi.org/10.1186/s13071-025-06800-4
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https://doi.org/10.1186/s13071-025-06800-4

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