An Optimized Liquid Chromatography–Mass Spectrometry Method for Ganglioside Analysis in Cell Lines

An Optimized Liquid Chromatography–Mass Spectrometry Method for Ganglioside Analysis in Cell Lines

Gangliosides are glycosphingolipids composed of a sialylated glycan head group and a ceramide backbone. These anionic lipids form lipid rafts and play crucial roles in regulating various proteins involved in signal transduction, adhesion, and cell–cell recognition. Neuroblastoma, a pediatric cancer...

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Main Authors: Akeem Sanni, Andrew I. Bennett, Yifan Huang, Isabella Gidi, Moyinoluwa Adeniyi, Judith Nwaiwu, Min H. Kang, Michelle E. Keyel, ChongFeng Gao, C. Patrick Reynolds, Brian Haab, Yehia Mechref
Format: Article
Language:English
Published: MDPI AG 2024-10-01
Series:Cells
Subjects:
gangliosides
ZIC-HILIC
LC-MS
neuroblastoma
Online Access:https://www.mdpi.com/2073-4409/13/19/1640
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