Riboflavin kinase binds and activates inducible nitric oxide synthase to reprogram macrophage polarization

Riboflavin kinase binds and activates inducible nitric oxide synthase to reprogram macrophage polarization

Riboflavin kinase (RFK) is essential in riboflavin metabolism, converting riboflavin to flavin mononucleotide (FMN), which is further processed to flavin adenine dinucleotide (FAD). While RFK enhances macrophage phagocytosis of Listeria monocytogenes, its role in macrophage polarization is not well...

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Main Authors: Xiao Shan, Zemin Ji, Baochen Wang, Yanan Zhang, Hongyuan Dong, Weijia Jing, Yanzhao Zhou, Penghui Hu, Yan Cui, Zihan Li, Sujun Yu, Jinxue Zhou, Ting Wang, Long Shen, Yuping Liu, Qiujing Yu
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Redox Biology
Subjects:
Riboflavin kinase
Inducible nitric oxide synthase
Macrophage polarization
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231724003914
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