The Niemann–Pick C1 Protein of Patients with Hepatocellular Carcinoma Is Associated with Survival Time in Males and Tumor Size in Females

The Niemann–Pick C1 Protein of Patients with Hepatocellular Carcinoma Is Associated with Survival Time in Males and Tumor Size in Females

<b>Background/Objectives:</b> The Niemann–Pick C1 (NPC1) protein regulates cellular cholesterol homeostasis, which is disrupted in hepatocellular carcinoma (HCC). Sex differences in cholesterol metabolism may also be related to NPC1 expression in HCC. A sex-specific analysis was, therefo...

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Bibliographic Details
Main Authors: Florian Weber, Katja Evert, Alexander Scheiter, Sophie von Sachsen-Coburg, Kirsten Utpatel, Christa Buechler
Format: Article
Language:English
Published: MDPI AG 2025-07-01
Series:Biomedicines
Subjects:
disease etiology
sex
UICC score
survival
Online Access:https://www.mdpi.com/2227-9059/13/7/1707
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