Long-term disease control in dedifferentiated liposarcoma: a case report on trabectedin priming followed by PD-1 inhibition

Long-term disease control in dedifferentiated liposarcoma: a case report on trabectedin priming followed by PD-1 inhibition

BackgroundDedifferentiated liposarcoma (DDLPS) is a rare mesenchymal cancer originating from the adipose tissue, with poor survival rates for most patients, highlighting the critical need for novel treatment options.Case descriptionThis report examines the efficacy and safety of sequential pre-treat...

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Bibliographic Details
Main Authors: Johannes M. Waldschmidt, Lukas Haug, Christine Riedhammer, Christoph K. W. Deinzer, Marcus Zimmermann, Anke Heidemeier, Peter Raab, Maximilian Rudert, Anne Hendricks, Johan F. Lock, Viktoria Buck, Andreas Rosenwald, Hermann Einsele, Peter Reichardt, Volker Kunzmann, Armin Wiegering, Daniel Pink, K. Martin Kortüm
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Oncology
Subjects:
sarcoma
dedifferentiated liposarcoma
checkpoint inhibition
PD-1
immune microenvironment
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2024.1518775/full
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https://www.frontiersin.org/articles/10.3389/fonc.2024.1518775/full

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