Combination of antiangiogenic and systemic therapy in advanced non-small cell lung cancer: before and after progression to leptomeningeal metastasis

Abstract Leptomeningeal metastasis (LM) is the most devastating complication of non-small cell lung cancer (NSCLC), and its incidence is increasing. We investigated the survival outcomes of patients with NSCLC who received combined antiangiogenic and systemic therapies before and after LM progressio...

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Bibliographic Details
Main Authors: Xiao-dan Zhu, Re-ha-ti Amanjiaoer, Yan-li Shen, Na Li, Mi-hray Abdurazik, Chun-ling Liu, Gang Sun
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Scientific Reports
Subjects:
Online Access:https://doi.org/10.1038/s41598-025-91922-z
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