Synergistic Effect of Hyperglycemia and Suppression on Adult Mouse Islet Beta Cell Replication

The complementary role of hyperglycemia and suppression on islet beta cell regeneration was investigated in a syngeneic mouse model. gene silencing was performed by infecting islets of C57BL/6 with shRNA lentiviral particles. At 54 hours after viral infection, protein content in cultured targetin...

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Bibliographic Details
Main Authors: Szu-Tah Chen, Shin-Huei Fu, Samuel Hsu, Yu-Yao Huang, Brend Ray-Sea Hsu
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:International Journal of Endocrinology
Online Access:http://dx.doi.org/10.1155/2012/417390
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