Cancer phylogenetic inference using copy number alterations detected from DNA sequencing data

Cancer phylogenetic inference using copy number alterations detected from DNA sequencing data

Cancer is an evolutionary process involving the accumulation of diverse somatic mutations and clonal evolution over time. Phylogenetic inference from samples obtained from an individual patient offers a powerful approach to unraveling the intricate evolutionary history of cancer and provides insight...

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Bibliographic Details
Main Author: Bingxin Lu
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Cancer Pathogenesis and Therapy
Subjects:
Clonal evolution
Phylogenetic inference
Somatic mutation
Copy number change
Chromosomal instability
Online Access:http://www.sciencedirect.com/science/article/pii/S2949713224000272
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