Tuning VSV-G Expression Improves Baculovirus Integrity, Stability and Mammalian Cell Transduction Efficiency

Tuning VSV-G Expression Improves Baculovirus Integrity, Stability and Mammalian Cell Transduction Efficiency

Baculoviral vectors (BVs) derived from <i>Autographa californica</i> multiple nucleopolyhedrovirus (AcMNPV) are an attractive tool for multigene delivery in mammalian cells, which is particularly relevant for CRISPR technologies. Most applications in mammalian cells rely on BVs that are...

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Bibliographic Details
Main Authors: Martina Mattioli, Renata A. Raele, Gunjan Gautam, Ufuk Borucu, Christiane Schaffitzel, Francesco Aulicino, Imre Berger
Format: Article
Language:English
Published: MDPI AG 2024-09-01
Series:Viruses
Subjects:
baculovirus
pseudotyping
VSV-G
AcMNPV
gene delivery
viral vector
Online Access:https://www.mdpi.com/1999-4915/16/9/1475
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