Chlorinated perfluoroalkyl ether sulfonate impairs proliferation and differentiation of neural stem cells via oxidative stress

Chlorinated perfluoroalkyl ether sulfonate impairs proliferation and differentiation of neural stem cells via oxidative stress

BackgroundChlorinated perfluoroalkyl ether sulfonate Cl-PFAES, trade name F-53B, a novel per- and polyfluoroalkyl substance (PFAS), has been shown to induce multi-organ toxicity in humans and cross the blood-brain barrier. However, its toxic effects and underlying mechanisms on neural stem cells (NS...

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Bibliographic Details
Main Authors: Yaxin HAN, Longfei FENG, Zhijun ZHOU, Xiuli CHANG
Format: Article
Language:English
Published: Editorial Committee of Journal of Environmental and Occupational Medicine 2025-06-01
Series:环境与职业医学
Subjects:
chlorinated perfluoroalkyl ether sulfonate
oxidative stress
neural stem cell
mitophagy
neurotoxicity
Online Access:http://www.jeom.org/article/cn/10.11836/JEOM25077
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