Adenoviral infection in children admitted with severe acute respiratory infection at tertiary care hospital from North India: A case series
There has been a recent surge in adenoviral infections with poor outcomes. This case series describes the clinical profile and outcome of 38 children admitted with adenovirus infection with severe acute respiratory illness (SARI). The majority (68.4%) were infants, 25 (65.7%) were immunocompetent, a...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2024-09-01
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| Series: | Journal of Pediatric Critical Care |
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| Online Access: | https://journals.lww.com/10.4103/jpcc.jpcc_46_24 |
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| author | Rajarshi Bera Pallavi Pallavi Sonal Saxena Shashi Chawla Urmila Jhamb Romit Saxena |
| author_facet | Rajarshi Bera Pallavi Pallavi Sonal Saxena Shashi Chawla Urmila Jhamb Romit Saxena |
| author_sort | Rajarshi Bera |
| collection | DOAJ |
| description | There has been a recent surge in adenoviral infections with poor outcomes. This case series describes the clinical profile and outcome of 38 children admitted with adenovirus infection with severe acute respiratory illness (SARI). The majority (68.4%) were infants, 25 (65.7%) were immunocompetent, and 13 (34.2%) had an underlying comorbidity. Twenty-seven (71%) patients required mechanical ventilation and 5 (13.1%) were managed on a heated high-flow nasal cannula. Nine (23.6%) children developed acute respiratory distress syndrome and four (10.5%) cases developed postinfectious bronchiolitis obliterans (PIBO). The median duration of mechanical ventilation was 24 days interquartile range [11.5–34.5] days. Eleven (28.9%) children in the study population expired. |
| format | Article |
| id | doaj-art-db5c284742684fe1adf8a1c47d2e13db |
| institution | Kabale University |
| issn | 2349-6592 2455-7099 |
| language | English |
| publishDate | 2024-09-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Pediatric Critical Care |
| spelling | doaj-art-db5c284742684fe1adf8a1c47d2e13db2025-01-23T06:04:10ZengWolters Kluwer Medknow PublicationsJournal of Pediatric Critical Care2349-65922455-70992024-09-0111523323710.4103/jpcc.jpcc_46_24Adenoviral infection in children admitted with severe acute respiratory infection at tertiary care hospital from North India: A case seriesRajarshi BeraPallavi PallaviSonal SaxenaShashi ChawlaUrmila JhambRomit SaxenaThere has been a recent surge in adenoviral infections with poor outcomes. This case series describes the clinical profile and outcome of 38 children admitted with adenovirus infection with severe acute respiratory illness (SARI). The majority (68.4%) were infants, 25 (65.7%) were immunocompetent, and 13 (34.2%) had an underlying comorbidity. Twenty-seven (71%) patients required mechanical ventilation and 5 (13.1%) were managed on a heated high-flow nasal cannula. Nine (23.6%) children developed acute respiratory distress syndrome and four (10.5%) cases developed postinfectious bronchiolitis obliterans (PIBO). The median duration of mechanical ventilation was 24 days interquartile range [11.5–34.5] days. Eleven (28.9%) children in the study population expired.https://journals.lww.com/10.4103/jpcc.jpcc_46_24clinical profilehuman adenoviruspediatric intensive care unitpolymerase chain reactionsevere acute respiratory illness (sari) |
| spellingShingle | Rajarshi Bera Pallavi Pallavi Sonal Saxena Shashi Chawla Urmila Jhamb Romit Saxena Adenoviral infection in children admitted with severe acute respiratory infection at tertiary care hospital from North India: A case series Journal of Pediatric Critical Care clinical profile human adenovirus pediatric intensive care unit polymerase chain reaction severe acute respiratory illness (sari) |
| title | Adenoviral infection in children admitted with severe acute respiratory infection at tertiary care hospital from North India: A case series |
| title_full | Adenoviral infection in children admitted with severe acute respiratory infection at tertiary care hospital from North India: A case series |
| title_fullStr | Adenoviral infection in children admitted with severe acute respiratory infection at tertiary care hospital from North India: A case series |
| title_full_unstemmed | Adenoviral infection in children admitted with severe acute respiratory infection at tertiary care hospital from North India: A case series |
| title_short | Adenoviral infection in children admitted with severe acute respiratory infection at tertiary care hospital from North India: A case series |
| title_sort | adenoviral infection in children admitted with severe acute respiratory infection at tertiary care hospital from north india a case series |
| topic | clinical profile human adenovirus pediatric intensive care unit polymerase chain reaction severe acute respiratory illness (sari) |
| url | https://journals.lww.com/10.4103/jpcc.jpcc_46_24 |
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