TIGIT immunosuppressive role in female reproductive system malignant neoplasms: from mechanism to therapy

TIGIT immunosuppressive role in female reproductive system malignant neoplasms: from mechanism to therapy

Introduction. Malignant neoplasms of the female reproductive system (ovarian, endometrial, and cervical cancers) account for a significant proportion of female oncology morbidity and mortality. Standard treatment methods, including surgery, chemotherapy, and radiotherapy, show limited efficacy in re...

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Main Authors: A. U. Khamadyanova, A. I. Romanova, A. N. Sklyar, A. P. Yamilova, M. G. Miranda Planas, G. D. Galeeva, S. R. Khakimov, A. A. Yakubov, S. K. Bikinyaev, Sh. M. Mammaev, A. A. Vardanyan, P. A. Kantaeva, T. R. Algirieva
Format: Article
Language:Russian
Published: IRBIS LLC 2020-04-01
Series:Акушерство, гинекология и репродукция
Subjects:
t-cell immunoglobulin and itim domain
tigit
immunotherapy
immune checkpoints
gynecologic malignancies
ovarian cancer
endometrial cancer
cervical cancer
Online Access:https://www.gynecology.su/jour/article/view/2483
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