Prognostic Factors of Functional Recovery from Left Hemispheric Stroke

Although lateralization of the brain affects some specialized cortical functions, there are still limited data to address its influence on clinically important outcomes. This study aimed to reveal the prognostic variables that relate to functional recovery in stroke patients with a left-sided hemisp...

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Main Authors: Siriphan Kongsawasdi, Jakkrit Klaphajone, Kanokwan Watcharasaksilp, Pakorn Wivatvongvana
Format: Article
Language:English
Published: Wiley 2018-01-01
Series:The Scientific World Journal
Online Access:http://dx.doi.org/10.1155/2018/4708230
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author Siriphan Kongsawasdi
Jakkrit Klaphajone
Kanokwan Watcharasaksilp
Pakorn Wivatvongvana
author_facet Siriphan Kongsawasdi
Jakkrit Klaphajone
Kanokwan Watcharasaksilp
Pakorn Wivatvongvana
author_sort Siriphan Kongsawasdi
collection DOAJ
description Although lateralization of the brain affects some specialized cortical functions, there are still limited data to address its influence on clinically important outcomes. This study aimed to reveal the prognostic variables that relate to functional recovery in stroke patients with a left-sided hemispheric lesion during 6 months of follow-up. Data from 167 left-sided and 183 right-sided hemispheric strokes were reviewed retrospectively. Outcomes in this study included walking capacity and functional recovery, assessed by the modified Rankin Scale (mRS). In order to obtain independent predictive variables, this study used the step-backward method of multivariable regression analysis of parameters. The final model demonstrated that motor function of the hemiparetic leg was the strongest independent predictor for both walking ability and functional recovery (risk ratio (RR) of 2.41, 95% CI: 1.61–3.60, and p<0.001 and RR of 1.83, 95% CI: 1.03–3.26, and p=0.04, resp.). Therefore, lateralization did not seem to be involved. Understanding predictable variables that are associated with recovery can guide the rehabilitation team in setting priority and appropriate treatment for stroke patients.
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institution Kabale University
issn 2356-6140
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language English
publishDate 2018-01-01
publisher Wiley
record_format Article
series The Scientific World Journal
spelling doaj-art-dad73b403d204cf9be9cf78f37ada3a22025-02-03T06:48:39ZengWileyThe Scientific World Journal2356-61401537-744X2018-01-01201810.1155/2018/47082304708230Prognostic Factors of Functional Recovery from Left Hemispheric StrokeSiriphan Kongsawasdi0Jakkrit Klaphajone1Kanokwan Watcharasaksilp2Pakorn Wivatvongvana3Clinical Epidemiology Program, Faculty of Medicine, Chiang Mai University, Chiang Mai, ThailandDepartment of Rehabilitation Medicine, Faculty of Medicine, Chiang Mai University, Chiang Mai, ThailandDepartment of Internal Medicine, Faculty of Medicine, Chiang Mai University, Chiang Mai, ThailandDepartment of Rehabilitation Medicine, Faculty of Medicine, Chiang Mai University, Chiang Mai, ThailandAlthough lateralization of the brain affects some specialized cortical functions, there are still limited data to address its influence on clinically important outcomes. This study aimed to reveal the prognostic variables that relate to functional recovery in stroke patients with a left-sided hemispheric lesion during 6 months of follow-up. Data from 167 left-sided and 183 right-sided hemispheric strokes were reviewed retrospectively. Outcomes in this study included walking capacity and functional recovery, assessed by the modified Rankin Scale (mRS). In order to obtain independent predictive variables, this study used the step-backward method of multivariable regression analysis of parameters. The final model demonstrated that motor function of the hemiparetic leg was the strongest independent predictor for both walking ability and functional recovery (risk ratio (RR) of 2.41, 95% CI: 1.61–3.60, and p<0.001 and RR of 1.83, 95% CI: 1.03–3.26, and p=0.04, resp.). Therefore, lateralization did not seem to be involved. Understanding predictable variables that are associated with recovery can guide the rehabilitation team in setting priority and appropriate treatment for stroke patients.http://dx.doi.org/10.1155/2018/4708230
spellingShingle Siriphan Kongsawasdi
Jakkrit Klaphajone
Kanokwan Watcharasaksilp
Pakorn Wivatvongvana
Prognostic Factors of Functional Recovery from Left Hemispheric Stroke
The Scientific World Journal
title Prognostic Factors of Functional Recovery from Left Hemispheric Stroke
title_full Prognostic Factors of Functional Recovery from Left Hemispheric Stroke
title_fullStr Prognostic Factors of Functional Recovery from Left Hemispheric Stroke
title_full_unstemmed Prognostic Factors of Functional Recovery from Left Hemispheric Stroke
title_short Prognostic Factors of Functional Recovery from Left Hemispheric Stroke
title_sort prognostic factors of functional recovery from left hemispheric stroke
url http://dx.doi.org/10.1155/2018/4708230
work_keys_str_mv AT siriphankongsawasdi prognosticfactorsoffunctionalrecoveryfromlefthemisphericstroke
AT jakkritklaphajone prognosticfactorsoffunctionalrecoveryfromlefthemisphericstroke
AT kanokwanwatcharasaksilp prognosticfactorsoffunctionalrecoveryfromlefthemisphericstroke
AT pakornwivatvongvana prognosticfactorsoffunctionalrecoveryfromlefthemisphericstroke