Reconstructing skeletal homeostasis through allogeneic hematopoietic stem cell transplantation in myelofibrosis

Abstract Myeloproliferative neoplasm-associated myelofibrosis is a clonal stem cell process characterized by pronounced bone marrow fibrosis associated with extramedullary hematopoiesis and splenomegaly. Allogeneic hematopoietic stem cell transplantation (allo-HSCT) represents the only curative trea...

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Main Authors: Mathias Schäfersküpper, Alexander Simon, Timur A. Yorgan, Felix N. von Brackel, Maximilian M. Delsmann, Anke Baranowsky, Nico Gagelmann, Francis Ayuk, Thorsten Schinke, Michael Amling, Nicolaus Kröger, Tim Rolvien
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-55915-w
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