Determination of the Anti-Escherichial Activity of the Pyrimidine Derivative 3-[2-[(4,6-dimethylpyrimidin-2- yl)amino]-2-oxoethyl]quinazolin-4(3H)-one

Determination of the Anti-Escherichial Activity of the Pyrimidine Derivative 3-[2-[(4,6-dimethylpyrimidin-2- yl)amino]-2-oxoethyl]quinazolin-4(3H)-one

The aim of this study was to investigate the antimicrobial activity of the pyrimidine derivative 3-[2-[(4,6-dimethylpyrimidin-2-yl)amino]-2-oxoethyl]quinazolin-4(3H)-one against Escherichia coli. The study of antimicrobial activity was carried out in vitro by serial dilutions of the pyrimidine compo...

Full description

Saved in:

Bibliographic Details
Main Authors:	A. A. Tsibizova, A. L. Yasenyavskaya, I. N. Tyurenkov, А. А. Ozerov, M. А. Samotrueva
Format:	Article
Language:	Russian
Published:	LLC "Publishing House OKI" 2023-12-01
Series:	Антибиотики и Химиотерапия
Subjects:	escherichia coli generalized escherichial infection bactericidal activity antimicrobial activity
Online Access:	https://www.antibiotics-chemotherapy.ru/jour/article/view/1057
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Study of the Anti-klebsiella Activity of Quinazoline Compounds Containing a Piperazine Ring
by: A. A. Tsibizova, et al.
Published: (2024-11-01)

Evaluation of Antimicrobial Activity of a Pyrimidine Derivative Against <i>Staphylococcus Aureus</i>
by: A. A. TSIBIZOVA, et al.
Published: (2022-09-01)

ANTIMICROBIAL ACTIVITY STUDY OF NEW QUINAZOLIN-4(3H)-ONES AGAINST STAPHYLOCOCCUS AUREUS AND STREPTOCOCCUS PNEUMONIAE
by: M. A. Samotrueva, et al.
Published: (2021-09-01)

Screening Studies of the Antimicrobial Activity of the Pyrimidine Compound 2,2-[6-Bromo-2,4-Dioxoquinazoline-1,3(2H)diyl]bis(N-Carbamimidoylacetamide)
by: A. A. Tsibizova, et al.
Published: (2024-04-01)

STUDY OF THE STABILITY OF THE SUBSTANCE 3-[2-(4-PHENYL-1-PIPERAZINO)-2-OXOETHYL]QUINAZOLINE-4(3Н)-ONE UNDER STRESSFUL CONDITIONS
by: T. A. Gendugov, et al.
Published: (2021-01-01)

Assessment of Acute Toxicity of Quinazoline Derivative 3-[2-oxo-2-(4-Phenylpiperazine-1-yl)Ethyl]quinazoline-4(3h)-oh Active against Opportunistic Microorganisms
by: N. M. Gabitova, et al.
Published: (2023-07-01)

Evaluation of the Antistaphylococcal Activity of the Pyrimidine Derivative
by: A. A. Tsibizova, et al.
Published: (2023-09-01)

Effect of a pyrimidine derivative on the level of cytokines in conditions of streptococcal wound infection
by: A. A. Tsibizova, et al.
Published: (2024-01-01)

2-([1,2,4]triazolo[1,5-c]quinazolin-2-yl-)alkyl-(alkaryl-, aryl-)-amines and their derivatives. (3Н-quinazolin-4-yliden)hydrazides (1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)alkyl-(alkaryl-, aryl-)carboxylic acids: features of synthesis, modification and ant
by: Yu. V. Martynenko, et al.
Published: (2016-08-01)

Results of Preclinical Studies of 4-(2-(4-nitrophenyl)-2-oxoethyl)-1-(thietane-3-yl)-1H-1,2,4-triazole-4-th Bromide in Relation to the Hemostasis System <i>in vivo</i>
by: Y. Wang, et al.
Published: (2024-03-01)

Diuretic activity of 2-((4-amino-5-R-4H-1,2,4-triazole-3-yl)thio)acetohydrazides
by: D. M. Danilchenko, et al.
Published: (2017-08-01)

4-phenyl-5-((pyrimidin-2-ylthio)methyl)-1,2,4-triazole-3-thiol as a platform for the synthesis of unsymmetrical disulfides
by: Yu. V. Karpenko, et al.
Published: (2025-03-01)

Antipyretic action of the new hydrazides 2 - (5 - (adamantane-1-yl)-4-r-1 ,2,4-triazol-3-ylthio)acetate
by: E. S. Pruglo, et al.
Published: (2013-06-01)

In silico study of biological activity of 2-[5-(furan-2-yl)-4-phenyl-4n-1,2,4-triazol-3-ylthio]-1-(4-chlorophenylethanone)
by: N. M. Borysenko, et al.
Published: (2025-06-01)

TOXICITY AND ANTIMICROBIAL ACTIVITY OF 6-CHLORO-2,4-DIAMINO- PYRIMIDINE
by: Rana A. Faaz, et al.
Published: (2015-06-01)

Actoprotective activity of 6-monosubstituted 3-R-6,7-dihydro-2H-[1,2,4]triazino-[2,3-c]quinazoline-2-ones
by: O. S. Kolomoets, et al.
Published: (2016-12-01)

3'-R-Spiro[cycloalkyl-1(2), (hetaryl-3(4), 6'-[1,2,4]triazino[2,3-c]quinazoline]-2'(7'H)-2-оnes as a perspective class of compounds with actoprotective activity
by: O. S. Kolomoets, et al.
Published: (2017-04-01)

Investigation of growth stimulating activity of 2-heteryl-[1,2,4]triazolo [1,5-c]quinazolines and products of its nucleophilic degradation
by: A. K. Bilyi, et al.
Published: (2013-02-01)

Assessment of Antimycobacterial Activity of Newly Synthesized Pyrimidine Derivatives Against Mycobacterium tuberculosis
by: M. A. Samotrueva, et al.
Published: (2022-08-01)

Nrf2-dependent effects of CDDO-Me on bactericidal activity in macrophage infection models
by: Therese B. Deramaudt, et al.
Published: (2025-05-01)

Methodology for prediction of anticancer action of (2-oxo-2H-[1,2,4]¬triazino[2,3-c]-quinazolin-6-yl)thiones via QSAR and docking studies
by: I. S. Nosulenko, et al.
Published: (2015-02-01)

Fe3O4@SiO2-SnCl4-promoted synthesis, cytotoxic evaluation, molecular docking, and MD simulation of some indenopyrido[2,3-d]pyrimidine derivatives
by: Leila Emami, et al.
Published: (2025-05-01)

Actoprotective activity of 2-(4-r-3-(thiophen-2-yl)-4h-1,2,4-triazol-3-ylthio) acetic acid
by: V. O. Salionov, et al.
Published: (2017-03-01)

Synthesis and Antibacterial Activity of 3-(Substituted)-2-(4-oxo-2-phenylquinazolin-3(4H)-ylamino)quinazolin-4(3H)-one
by: Ramgopal Appani, et al.
Published: (2016-01-01)

Time-kill properties of citrus peel essential oils and constituents against foodborne pathogens
by: Lee Je-Hyuk
Published: (2025-06-01)

BACTERICIDAL ACTIVITY OF LEUKOCYTES IN PULMONARY TUBERCULOSIS PATIENTS
by: M. E. Dyakova, et al.
Published: (2017-11-01)

2-([1,2,4]triazolo[1,5-c]quinazoline-2-yl-)alkyl-(alkaryl-,aryl-)-amines and their derivatives. Message 2. The synthesis of (3Н-quinazoline-4-ylidene)hydrazides N-protected aminoacids, using a variety of amine-protecting approaches. Physical-chemical prop
by: Yu. V. Martynenko, et al.
Published: (2018-06-01)

The rate of liver impairment, character of bacteremia and serum bactericidal activity in patients with cirrhosis
by: Krutikov S.N., et al.
Published: (2014-06-01)

The study of UV-spectra of the sodium (3-oxo-3,4-dihydro-2H-[1,2,4]triazino[4,3-c]quinazolin-4-yl)acetate
by: О. V. Kryvoshey
Published: (2016-04-01)

In silico and in vivo Study of the Anti-Inflammatory Activity of Azomethine Derivatives of 2-amino-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide and 2-substituted 5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidine-4(3H)-one
by: Chiriapkin, A.S., et al.
Published: (2025-02-01)

Acute toxicity of 3-(2-, 3-fluorophenyl)-6-(aryl-, hetaryl)-[1,2,4]triazole[3,4-b][1,3,4]thiadiazoles
by: O. A. Bihdan, et al.
Published: (2017-12-01)

Antimicrobial and antifungal activity of new 4-(5-((5-(alkylthio)-4-R-4H-1,2,4-triazole-3-yl)thio)-1H-1,2,4-triazole-3-yl)pyridines
by: Ye. O. Karpun, et al.
Published: (2020-11-01)

Overcoming the protective functions of macrophages by Streptococcus pyogenes virulence factors
by: I. S. Freydlin, et al.
Published: (2019-05-01)

Studies on the method of controlling enzymatic reaction time of acetylene reduction in determining associative nitrogenase activity of associative system
by: JI Tian-wei, et al.
Published: (2003-07-01)

Contezolid Harbored Equivalent Efficacy to Linezolid in Tuberculosis Treatment in a Prospective and Randomized Early Bactericidal Activity Study
by: Jiang G, et al.
Published: (2025-01-01)

The antimicrobial activity of exogeno us anionic phospholipids against Mycobacterium tuberculosis and Escherichia coli
by: Yu. L. Mikulovich, et al.
Published: (2016-06-01)

A study of antimicrobial and antifungal activity of 2-((5-(2-bromophenyl)-4-substituted-4H-1,2,4-triazol-3-yl)thio)acetates
by: A. A. Safonov, et al.
Published: (2020-11-01)

Prediction of biological activity of 4-(3,4 dimethoxybenzylidene)amino)-5-(2-fluorophenyl)-4H-1,2,4 triazole-3-thiol
by: V. P. Martynyshyn, et al.
Published: (2024-12-01)

Synthesis, antimicrobial and antifungal activity of 3-(2-bromophenyl)-5-(alkylthio)-4-phenyl-4H-1,2,4-triazoles
by: A. A. Safonov, et al.
Published: (2022-12-01)

Crystal structure and Hirshfeld surface analyses, intermolecular interaction energies and energy frameworks of methyl 6-amino-5-cyano-2-(2-methoxy-2-oxoethyl)-4-(4-nitrophenyl)-4H-pyran-3-carboxylate
by: Farid N. Naghiyev, et al.
Published: (2025-04-01)